Live Telecast, "STEM CELL THERAPY & NEUROLOGICAL DISORDERS" on 21st April 2018 at 3.30 PM on Z-24TAAS_HITGUJ By Dr. Anant Bagul   :*: Upcomming Events: “2ND INTERNATIONAL REGENERATIVE MEDICINE CONCLAVE ON 13TH MAY 2018”  

Multiple Sclerosis

Multiple sclerosis are characterized by gradual and progressive degeneration and death of motor neurons. Normally, messages from nerve cells in the brain, or upper motor neurons, are transmitted to nerve cells in the brain stem and spinal , known as lower motor neurons, and from there to skeletal muscles. Upper motor neurons direct the lower motor neurons to produce movements such as walking or chewing. Lower motor neurons control movement in the arms, legs, chest, face, throat, and tongue. Currently, there is no cure for MS.

Stem Cell is a science of regeneration to induce repair and regeneration of neurons , which was damaged due to various cause.
There are a number of advantages to using human stem cells that do not require immune suppression and which can help balance immune function by changing the genetics of the immune reactive cells.

Multiple Sclerosis research Multiple Sclerosis research
References:

Multiple Sclerosis reversed' with stem cell 11:57 30 January 2009 by Linda Geddes Three years later, 17 of the (24) patients had improved by at least one point on a standard disability scale, while none of the patients had deteriorated.
http://www.newscientist.com/article/dn16509-multiple-sclerosis-reversed-with-stem-cell.html

Bone Marrow Stem Cells Show Exciting Potential For Multiple Sclerosis clinical trial Medical News Today Article Date: 06 May 2010 - 1:00PDT
The procedure was well tolerated and the participants were followed up for a year. No serious adverse effects were encountered. The results of clinical scores were consistent with stable disease. The results of neurophysiological tests raised the possibility of benefit. (see below study).
http://www.medicalnewstoday.com/articles/187840.php

Multiple Sclerosis 'reversed' with stem cell11:57 30 January 2009 by Linda Geddes Three years later, 17 of the (24) patients had improved by at least one point on a standard disability scale, while none of the patients had deteriorated.
http://www.newscientist.com/article/dn16509-multiple-sclerosis-reversed-with-stem-cell.html

Safety and Feasibility of Autologous Bone Marrow Cellular in Relapsing-Progressive Multiple Sclerosis.
The lack of serious adverse effects and the suggestion of a beneficial effect in this small sample of patients with progressive disease justify conducting a larger phase II/III study C M Rice1, E A Mallam1, A L Whone1,2,3, P Walsh1, D J Brooks2, N Kane1, S R Butler3, D I Marks4 and N J Scolding1
Clinical Pharmacology & Therapeutics (2010) 87 6, 679–685. doi:10.1038/clpt.2010.44
http://www.nature.com/clpt/journal/v87/n6/full/clpt201044a.html

Early-Stage Multiple Sclerosis Reversed By Stem Cell Transplant
Medical News Today Article Date: 31 Jan 2009 – Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby" resetting" their immune systems.
http://www.medicalnewstoday.com/articles/137303.php

Stem Cell Transplant Study Shows Promise For Multiple Sclerosis
Article Date: 12 Jun 2009 - 3:00 PDT
“Some 81 percent of patients in the early phase study showed signs of improvement with the clinical trial. which used chemoresearch to destroy the immune system, and injections of the patient's bone marrow cells taken beforehand to rebuild it.”
http://www.medicalnewstoday.com/articles/153564.php

Early-Stage Multiple Sclerosis Reversed By Stem Cell Transplant
Medical News Today Article Date: 31 Jan 2009 - 0:00 PDT
"This is the first time we have turned the tide on this disease," said principal investigator Richard Burt, M.D. chief of immunoresearch for autoimmune diseases at the Feinberg School.
http://www.medicalnewstoday.com/articles/137303.php

Fat Tissue Stem Cells Offer Hope For Multiple Sclerosis clinical trial
Article Date: 24 Apr 2009 - 1:00 PDT
"All three patients in our study showed dramatic improvement in their condition after the course of SVF research.”
http://www.medicalnewstoday.com/articles/147420.php

Immune System Helps Transplanted Stem Cells Navigate In Central Nervous System Medical News Today
Article Date: 02 Jun 2010 - 5:00 PDT
"In this study, we've taken an important step by showing the navigational cues in an inflammatory environment like MS that guide stem cells,"
http://www.medicalnewstoday.com/articles/190645.php