Live Telecast, "STEM CELL THERAPY & NEUROLOGICAL DISORDERS" on 21st April 2018 at 3.30 PM on Z-24TAAS_HITGUJ By Dr. Anant Bagul   :*: Upcomming Events: “2ND INTERNATIONAL REGENERATIVE MEDICINE CONCLAVE ON 13TH MAY 2018”  

DMD - Limb Girdle

LGMD is a genetic disorder caused by absence of some proteins in muscle and leads to muscle degeneration.

c-FLIP protein, which is responsible for blocking the death of muscle cells, is not produced as it should in people with limb-girdle muscular dystrophy, and that the creation of the c-FLIP protein is controlled by another protein called calpain-3. According to the authors, this finding may have implications for other types of muscular dystrophy.

As you are aware that LGMD is a difficult question and lack of c-FLIP protein is our major concern, However use of driven mesenchymal cells will provide healthy genes and stem cell transplantation may reset up the blood-making function, decrease the serum CK level, restore the cFLIP in muscles, and improve the locomotive function of the LGMD patients.

If you want to know more information, you may refer to internet articles,

http://www.empowher.com/muscular-dystrophy/content/stem-cell-muscular-dystrophy/

http://www.vigendo.com/clinical trial/muscular-dystrophy/

http://healthcarenewsblog.com/india-stem-cell-for-limb-girdle-muscular-dystrophy/

http://www.unistemcells.com/en/patientstory/MD100816114824754.htm

http://www.unistemcells.com/en/clinical trial/md12653489.htm