Live Telecast, "STEM CELL THERAPY & NEUROLOGICAL DISORDERS" on 21st April 2018 at 3.30 PM on Z-24TAAS_HITGUJ By Dr. Anant Bagul   :*: Upcomming Events: “2ND INTERNATIONAL REGENERATIVE MEDICINE CONCLAVE ON 13TH MAY 2018”  

Collection and Processing

Bone marrow processing and quality testing

Prior to scheduling bone marrow collection you will be asked to fill out the patient consent form. This form grants explicit written permission for bone marrow collection.
You must discontinue using any blood diluting medications at least 10 days before your collection date.

It is advisable to consult your physician before discontinuing the use of blood diluting drugs.

On the fix, our team will be prepared to begin the collection procedure and try their best to make it comfortable for you.

When we greet you on collection day, we'll have everything prepared to begin the procedure. The physician will collect approximately 150 - 200 ml of bone marrow from your hip bone.

Stem cell collection is performed as an in-patient procedure under local / general anaesthesia in sterile conditions. During the collection, you will barely feel the needle insertion into your hip bone. Post the collection you may experience slight pain for 3-4 days and the area might appear like a ‘blue spot’. Normally, there are no other side effects.

Theoretically, there is a small risk of infection. We minimize this risk by working in a sterile environment. Within 48 hours, the stem cell samples are processed and quality tested by a highly specialized laboratory in totally sterile clean room conditions.

Since they are in sterile tubes they never come into contact with the air and the sample is thus protected from contamination.

Stem cells are introduced in cerebrospinal fluid via lumbar puncture. Since the cerebrospinal fluid circulates, stem cells are transported directly to the damaged tissue in the brain or the spinal cord.

Bone marrow processing and quality testing consists of

  • Stem cell isolation - stem cells are separated from the red blood cells and blood plasma
  • Stem cell counting
  • Stem cell vitality measurement
The entire procedure usually takes about 30 minutes. Immediately after clinical trial, you will spend about three or four hours laying in bed in our recovery room for observation. As with any minimally invasive intervention, intrathecal stem cell implantation carries a very small risk of infection. We minimize this risk by working in a sterile environment and by prescribing prophylactic antibiotics to you. If there are no complications, you can return home after 2 days.

For the clinical trial patient needs 2- 3 days admission during which his examinations and various investigations are conducted as per the International Council – Stem Cell Research protocol(IC-SCRT).
During the stem cell the stem cells are acquired by extraction of the bone marrow. The extracted material is sent to stem cell based biological Laboratory.

During processing the stem cells are separated according to the International Quality Control protocol. These stem cells are processed & followup will be done as per clinical trial protocol.

Improvement is evident from 8 weeks onwards to 1 year as stated according to the previous experiences and studies. Patient may need 2-3 follow up injections as per the improvement.

Possible Adverse Effects from the clinical trial
After the procedure, you might experience the following adverse effects.
Nausea
Headache
Backache and Leg pain

clinical trial advantages
Simple
Less invasive than surgery

research disadvantages
Less precise application

Follow-up
Once you have returned home, a member of our medical team will regularly monitor your progress via telephone and email. For your convenience, a telephone 'hotline' is always at your disposal.